奧貝膽酸由美國Intercept制藥公司研發成功，是二十年來*研發用于治療膽汁淤積性肝病的藥物。奧貝膽酸屬法尼醇X受體激動劑，通過活化法尼醇X受體，間接抑制細胞色素7A1（CYP7A1）的基因表達。由于CYP7A1是膽酸生物合成的限速酶，因此奧貝膽酸可以抑制膽酸合成，用于治療原發性膽汁性肝硬化和非酒精性脂肪性肝病。   

       深圳遠揚化學可提供奧貝膽酸申報所用全套雜質， 隨貨附CoA證書，HNMR，MS，HPLC圖譜，純度符合申報要求，奧貝膽酸雜質為我司優勢雜質，長期備有庫存，發貨快。如需奧貝膽酸雜質相關詳細信息，歡迎我司業務人員獲取~

       除自主品牌雜質對照品外，我司還代理英國NIBSC標準品，美國劍橋CIL同位素標準品，美國NIST標準物質，歐洲標準局IRMM標準物質，加拿大TRC標準品，TLC標準品，MOLCAN標準品，NRC標準品等，歡迎洽談。

附：奧貝膽酸雜質庫存雜質列表：

Obeticholic Acid

(4R)-4-((3R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 1

(R)-4-((3R,5S,6R,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 2

(R)-4-((3R,5S,6S,7S,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 3

(R)-4-((3R,5S,6S,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 4

(R)-4-((3R,5S,6S,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 5

(4R)-4-((3R,5S,6R,7R,9S,10S,13R,14S,17R)-6-ethyl-3-(((R)-4-((3R,5S,6R,7R,8S,9S,10S,13R,14S,17R)-6-ethyl-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoyl)oxy)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 6

(R)-4-((3R,5R,7S,8S,9S,10R,13R,14S,17R,E)-6-ethylidene-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 7

(R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-3,7-dioxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 8

(R)-methyl 4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate

Obeticholic Acid Impurity 9

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 10

(R)-4-((3R,5S,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoic acid

Obeticholic Acid Impurity 11

(R)-methyl 4-((3R,5S,6R,8S,9S,10S,13R,14S,17R)-6-ethyl-3-hydroxy-10,13-dimethyl-7-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanoate