目錄:杭州斯達(dá)特生物科技有限公司>>蛋白>>藥物靶點和Fc受體>> UA011107ZNRF3 His Tag Protein, Human
The transmembrane E3 ubiquitin ligase, Zinc and Ring Finger 3 （ZNRF3）, serves as a negative feedback regulator of Wnt signaling. ZNRF3 is associated with the Wnt receptor complex and inhibits Wnt signaling by promoting the turnover of Frizzled and LRP6. Additionally, ZNRF3 functions as a tumor suppressor in the intestinal stem cell compartment by inhibiting the Wnt signaling pathway.
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