鹽酸依特卡肽 1334237-71-6，KAI-4169

英文名：Etelcalcetide hydrochloride

(6R,9R,12R,15R,18R,21R,24S,29R)-24-Acetamido-1,29-diamino-12,15,18-tris(3-carbamimidamidopropyl)-6-carbamoyl-1-imino-9,21-dimethyl-8,11,14,17,20,23-hexaoxo-26,27-dithia-2,7,10,13,16,19,22-heptaazatriacontan-30-oic acid hydrochloride (1:1)

AMG 416

velcalcetide hydrochloride

etelcalcetide hydrochloride

KAI-4169

UNII:72PT5993DU

AMG-416

中文名：鹽酸依特卡肽

CAS：1334237-71-6

分子式：C38H73N21O10S2.xClH

分子量：1084.712

結構式：

***質量：1083.505737

描述：Etelcalcetide hydrochloride (AMG 416 hydrochloride) 是一種合成肽，有鈣敏感受體 (CaSR) 活化劑的作用。Etelcalcetide hydrochloride 可有效降低接受血液透析的繼發性甲狀旁腺功能亢進患者的甲狀旁腺*** (PTH) 濃度。

參考文獻：

[1]. Block GA, et al. Effect of Etelcalcetide vs Cinacalcet on Serum Parathyroid Hormone in Patients Receiving Hemodialysis With Secondary Hyperparathyroidism: A Randomized Clinical Trial. JAMA. 2017 Jan 10;317(2):156-164.

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鹽酸依特卡肽 1334237-71-6，KAI-4169