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ICG NHS ester;吲哚菁綠-琥珀酰亞胺酯； ICG-SE
閱讀：135 發(fā)布時(shí)間：2019-3-9| 提 供 商 | 陜西新研博美生物科技有限公司 | 資料大小 | 11.3KB |
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ICG NHS ester;吲哚菁綠-琥珀酰亞胺酯
英文名：ICG NHS ester; ICG-SE
中文名：吲哚菁綠-琥珀酰亞胺酯; 吲哚菁綠-活性脂
CAS: 1622335-40-3
分子式: C49H53N3O7S
分子量: 828.03
外觀：綠色粉末
溶解性：溶于DMSO或DMF
純度：95%
保存：-20避光
激發(fā)發(fā)射波長(zhǎng):785/821nm
結(jié)構(gòu)式：
產(chǎn)品描述：ICG is a NIR fluorescent substance which obtain license for clinical uses from US FDA(Food and Drug administration), along with Methylene Blue. It is used in Ophthalmologic angiography, liver function tests, solid tumor detection in surgical operation and angiography.
Because ICG effectively absorbs near infrared wavelength that is about 800nm and its absorption ratio for wavelength of visible light range is low, noises caused by Autofluorescence is low.
ICG NHS ester is a product that has the most representative NHS ester reactive group for labeling amine. Because it rapidly and high-specifically reacts to Primary amine (-NH2), it can label Protein containing amine (-NH2), Antibody and Amine-modified Oligonucleotide in a short time period.
近紅外熒光染料Near IRDyes激發(fā)和發(fā)射波長(zhǎng)和顏色圖：
ICG NHS ester的NHS可以和蛋白、多肽或抗體上面的NH2發(fā)生反應(yīng)鏈接到一起。
ICG-maleimide的馬來(lái)酰亞胺可以和蛋白、多肽、小分子或抗體上的SH巰基反應(yīng)連接。
ICG-Amine的NH2可以和蛋白、多肽小分子上面的NHS反應(yīng)連接起來(lái)。
ICG和PEG鏈接可在體內(nèi)長(zhǎng)循環(huán)。
ICG的活性基團(tuán)熒光染料：
ICG NHS ester
ICG-Vinylsulfone
ICG-Isothiocyanate
ICG-carboxlaic acid
ICG-maleimide
ICG-Amine
Sulfo ICG-NHSester
ICG和PEG修飾的產(chǎn)品：
ICG-PEG-NH2
ICG-PEG-MAL
ICG-PEG-NHS
ICG-PEG-COOH
ICG-PEG-Folate
ICG-PEG-N3
ICG-PEG-SH
ICG-PEG-DSPE