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目錄:上海貝博生物科技有限公司>>Primary Antibodies>> C1RL rabbit pAb

C1RL rabbit pAb
  • C1RL rabbit pAb
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更新時間:2025-07-15 15:02:49瀏覽次數:109評價

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SourceRabbitApplicationsWB
  • Source

    Rabbit

  • Applications

    WB,ELISA

  • Reactivity

    Human

  • Dilution

    WB 1:500-2000, ELISA 1:10000-20000

  • Storage

    -20°C/1 year

  • Specificity

    C1RL Polyclonal Antibody detects endogenous levels of C1RL

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    Synthesized peptide derived from human C1RL. at AA range: 371-420

  • Uniprot No

    Q9NZP8

  • Alternative names

    Complement C1r subcomponent-like protein (C1r-LP) (C1r-like protein) (EC 3.4.21.-) (C1r-like serine protease analog protein) (CLSPa)

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caution:Does not associate with the C1 complex. According to PubMed:15385675 doesn't cleave the proform of complement C1s.,function:Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum.,induction:Up-regulated in monocytes and dendritic cells (DC) undergoing maturation or activation.,similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 CUB domain.,similarity:Contains 1 peptidase S1 domain.,tissue specificity:Highly expressed in placenta, liver, kidney, pancreas, moderately in lung, spleen, prostate, ovary, colon, and PBL, and weakly in heart, skeletal muscle, thymus, testis, and small intestine. Expressed in PC-3 (prostate adenocarcinoma) and SK-OV-3 (ovary adenocarcinoma) cells, but not in LoVo and HT-29 (colon adenocarcinoma), SMMC7721 (hepatocellular carcinoma), CaoV-3 (ovary adenocarcinoma), HeLa (cervix epithelioid carcinoma), MCF-7 (breast adenocarcinoma), U251 (glioma) or A549 (lung carcinoma) cells. Widely expressed in myeloid leukemia cell lines, including K-562 (chronic myelogenous leukemia), THP-1 (myelomonocytic leukemia), HL-60 and NB4 (promyelocytic leukemia), and KG-1 (acute myelogenous leukemia) cells. Expressed mainly in the liver and in serum (at protein level).,

  • Other

    C1RL, C1RL

  • Concentration

    1 mg/ml

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