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Source

Rabbit

Applications

WB

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:1000-2000

Storage

-20°C/1 year

Specificity

The antibody detects endogenous Beclin-1 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Recombinant Protein of Beclin-1

Uniprot No

Q14457

Alternative names

BECN1; GT197; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197

Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Isotype

IgG

Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Other

BECN1, Beclin-1

Concentration

1 mg/ml