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Source

Rabbit

Applications

WB

Reactivity

Mouse,Rat,(H)

Dilution

WB: 1:1000-2000

Storage

-20°C/1 year

Specificity

The antibody detects endogenous beta 1 Sodium Potassium ATPase protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthetic Peptide of beta 1 Sodium Potassium ATPase

Uniprot No

P05026

Alternative names

Sodium/potassium-transporting ATPase subunit beta-1 (Sodium/potassium-dependent ATPase subunit beta-1)

Form

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Clonality

Polyclonal

Isotype

IgG

Background

ATPase Na+/K+ transporting subunit beta 1(ATP1B1) Homo sapiens The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript

Other

ATP1B1, Sodium/potassium-transporting ATPase subunit beta-1

Concentration

1 mg/ml