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Source

Mouse

Applications

IHC

Reactivity

Human,Rat,Mouse

Dilution

IHC 1:100-200

Storage

-20°C/1 year

Specificity

Beclin-1 protein detects endogenous levels of BECN1

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Synthetic Peptide of Beclin-1 at AA range of 110-190

Uniprot No

Q14457

Alternative names

BECN1

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Isotype

IgG

Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Other

BECN1, BECN1

Concentration

1 mg/ml