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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse

Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

BCL2L12 Polyclonal Antibody detects endogenous levels of BCL2L12 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from BCL2L12 . at AA range: 60-140

Uniprot No

Q9HB09

Alternative names

BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

BCL2 like 12(BCL2L12) Homo sapiens This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

Other

BCL2L12, Bcl-2-like protein 12

Mol.Wt (Da)

36821

Concentration

1 mg/ml