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Source

Rabbit

Applications

IHC,ELISA

Reactivity

Human

Dilution

IHC 1:50-200, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

The antibody detects endogenous ASPP1

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthetic peptide from human protein at AA range: 630-680

Uniprot No

Q96KQ4

Alternative names

Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

protein phosphatase 1 regulatory subunit 13B(PPP1R13B) Homo sapiens This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008],

Other

PPP1R13B ASPP1 KIAA0771, Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)

Concentration

1 mg/ml