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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB 1:500-2000, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

BMP-10 Polyclonal Antibody detects endogenous levels of BMP-10

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized peptide derived from BMP-10 at AA range: 361-410

Uniprot No

O95393

Alternative names

bone morphogenetic protein 10

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

bone morphogenetic protein 10(BMP10) Homo sapiens This gene encodes a secreted ligａnd of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which binds to the activin receptor-like kinase 1 (ALK1) and plays important roles in cardiovascular development including cardiomyocyte proliferation and regulation of heart size, closure of the ductus arteriosus, angiogenesis and ventricular trabeculation. [provided by RefSeq, Aug 2016],

Other

BMP10, BMP-10

Mol.Wt (Da)

48047

Concentration

1 mg/ml