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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human,Mouse,Rat

Dilution

WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

Uniprot No

Q9HCU9

Alternative names

BRMS1; Breast cancer metastasis-suppressor 1

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

breast cancer metastasis suppressor 1(BRMS1) Homo sapiens This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Other

BRMS1, Breast cancer metastasis-suppressor 1

Mol.Wt (Da)

28461

Concentration

1 mg/ml