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Source

Rabbit

Applications

IHC,ELISA

Reactivity

Human

Dilution

IHC: 1:100 - 1:300. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Phospho-Bcl-2 (T74) Polyclonal Antibody detects endogenous levels of Bcl-2 protein only when phosphorylated at T74.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthesized phospho-peptide around the phosphorylation site of human Bcl-2 (phospho Thr74)

Uniprot No

P10415

Alternative names

BCL2; Apoptosis regulator Bcl-2

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

BCL2, apoptosis regulator(BCL2) Homo sapiens This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

Other

BCL2, Apoptosis regulator Bcl-2

Mol.Wt (Da)

26266

Concentration

1 mg/ml