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目錄:上海貝博生物科技有限公司>>Primary Antibodies>> BRCA2 rabbit pAb

BRCA2 rabbit pAb
  • BRCA2 rabbit pAb
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SourceRabbitApplicationsIHC,ELISAReactivityHuman,RatDilutionIHC:1:100-1:300
  • Source

    Rabbit

  • Applications

    IHC,ELISA

  • Reactivity

    Human,Rat

  • Dilution

    IHC: 1:100 - 1:300. ELISA: 1:20000. Not yet tested in other applications.

  • Storage

    -20°C/1 year

  • Specificity

    BRCA2 Polyclonal Antibody detects endogenous levels of BRCA2 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human BRCA2. AA range:31-80

  • Uniprot No

    P51587

  • Alternative names

    BRCA2; FACD; FANCD1; Breast cancer type 2 susceptibility protein; Fanconi anemia group D1 protein

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    BRCA2, DNA repair associated(BRCA2) Homo sapiens Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008],

  • Other

    BRCA2, Breast cancer type 2 susceptibility protein

  • Mol.Wt (Da)

    384225

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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