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Source

Rabbit

Applications

WB

Reactivity

Human,Mouse

Dilution

WB 1:1000-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of Human Mouse Beclin-1 (phospho-Ser15)

Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen

Synthesized phosho peptide around human Beclin-1 (Ser15)

Uniprot No

Q14457

Alternative names

Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],

Other

BECN1 GT197, Beclin-1 (Ser15)

Concentration

1 mg/ml