Source

Rabbit

Applications

WB

Reactivity

Human, Mouse

Dilution

WB 1:500-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of ADA11 at Human/Mouse

Source/Purification

The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogen

Synthesized peptide derived from human ADA11

Uniprot No

O75078

Alternative names

Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like, disintegrin-like, and cysteine-rich protein) (MDC)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.327% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016],

Other

ADAM11 MDC, ADA11, Disintegrin and metalloproteinase domain-containing protein 11 (ADAM 11) (Metalloproteinase-like

Concentration

1 mg/ml