Source

Mouse/IgG1, Kappa

Applications

WB

Reactivity

Human

Dilution

WB 1:500-2000

Storage

-20°C/1 year

Specificity

This antibody detects endogenous levels of human Alpha-1-Fetoprotein(AFP)

Source/Purification

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Immunogen

Synthesized peptide derived from human Alpha-1-Fetoprotein(AFP)

Uniprot No

P02771

Alternative names

Alpha-fetoprotein (Alpha-1-fetoprotein) (Alpha-fetoglobulin)

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Monoclonal

Isotype

IgG

Background

alpha fetoprotein(AFP) Homo sapiens This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Jul 2008],

Other

AFP, Alpha-1-Fetoprotein(AFP)

Concentration

1 mg/ml