性做久久久久久坡多野结衣-性做久久久久久久久浪潮-性欲影院-性影院-国产精品线路一线路二-国产精品兄妹在线观看麻豆

Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human,Mouse,Rat,Monkey

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Catenin-β Polyclonal Antibody detects endogenous levels of Catenin-β protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human Catenin-beta. AA range:17-66

Uniprot No

P35222

Alternative names

CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

catenin beta 1(CTNNB1) Homo sapiens The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016],

Other

CTNNB1, Catenin beta-1

Mol.Wt (Da)

85497

Concentration

1 mg/ml