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Source

Rabbit

Applications

WB,IHC,IF,ELISA

Reactivity

Human,Mouse,Rat,Monkey

Dilution

WB: 1:500 - 1:2000. IHC: 1:100 - 1:300. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CB1 Polyclonal Antibody detects endogenous levels of CB1 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human CNR1. AA range:151-200

Uniprot No

P21554

Alternative names

CNR1; CNR; Cannabinoid receptor 1; CB-R; CB1; CANN6

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

cannabinoid receptor 1(CNR1) Homo sapiens This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, May 2009],

Other

CNR1, Cannabinoid receptor 1

Mol.Wt (Da)

52858

Concentration

1 mg/ml