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Source

Rabbit

Applications

WB,IHC,ELISA

Reactivity

Human,Mouse

Dilution

IHC: 100-300.WB: 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CD133 Polyclonal Antibody detects endogenous levels of CD133 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from the N-terminal region of human PROM1. AA range:41-90

Uniprot No

O43490

Alternative names

PROM1; Prominin-1; Antigen AC133; Prominin-like protein 1; CD133

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

prominin 1(PROM1) Homo sapiens This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],

Other

PROM1, Prominin-1

Mol.Wt (Da)

97202

Concentration

1 mg/ml