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Source

Rabbit

Applications

WB,IF,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. IF: 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

CD137 Polyclonal Antibody detects endogenous levels of CD137 protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human TNFRSF9. AA range:101-150

Uniprot No

Q07011

Alternative names

TNFRSF9; CD137; ILA; Tumor necrosis factor receptor superfamily member 9; 4-1BB ligａnd receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD antigen CD137

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

TNF receptor superfamily member 9(TNFRSF9) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008],

Other

TNFRSF9, Tumor necrosis factor receptor superfamily member 9

Mol.Wt (Da)

27899

Concentration

1 mg/ml