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Source

Rabbit

Applications

IHC,ELISA

Reactivity

Human

Dilution

IHC 1:50-200, ELISA 1:10000-20000

Storage

-20°C/1 year

Specificity

The antibody detects endogenous CD1A/B

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

Synthetic peptide from human protein at AA range: 220-270

Uniprot No

P06126/P29016

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

CD1a molecule(CD1A) Homo sapiens This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Other

CD1A CD1B, T-cell surface glycoprotein CD1A/B (CD antigen CD1A/B)

Concentration

1 mg/ml