ICG-001(ICG 001); (S,S)-ICG 001;(6S,9aS)-六氫-6-[(4-羥基苯基)甲基]-8-(1-萘基甲基)-4,7-二氧代-N-(苯甲基)-2H-吡嗪并[1,2-a]嘧啶-1(6H)-甲酰胺;780757-88-2
僅用于工業應用或科學研究,不可用于人類或動物的臨床診斷或治療,非藥用.ICG-001 is an inhibitor of β-catenin/TCF mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC50 of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction.ICG-001 是 β-catenin/TCF 介導的轉錄抑制劑