Product Name 

ACADVL protein

Product type 

Proteins and Peptides

Peptide 

Recombinant full length Human ACADVL （amino acids 41-655） with an N terminal His tag; 636 amino acids including tag, MWt 68.5kDa. （UniProt P49748）.

BLAST 'MGSSHHH HHHSSGLVPR GSHMAG GAAQLALDKS DSHPSDALTR KKPAKAESKS FAVGMFKGQL TTDQVFPYPS VLNEEQTQFL KELVEPVSRF FEEVNDPAKN DALEMVEETT WQGLKELGAF GLQVPSELGG VGLCNTQYAR LVEIVGMHDL GVGITLGAHQ SIGFKGILLF GTKAQKEKYL PKLASGETVA AFCLTEPSSG SDAASIRTSA VPSPCGKYYT LNGSKLWISN GGLADIFTVF AKTPVTDPAT GAVKEKITAF VVERGFGGIT HGPPEKKMGI KASNTAEVFF DGVRVPSENV LGEVGSGFKV AMHILNNGRF GMAAALAGTM RGIIAKAVDH ATNRTQFGEK IHNFGLIQEK LARMVMLQYV TESMAYMVSA NMDQGATDFQ IEAAISKIFG SEAAWKVTDE CIQIMGGMGF MKEPGVERVL RDLRIFRIFE GTNDILRLFV ALQGCMDKGK ELSGLGSALK NPFGNAGLLL GEAGKQLRRR AGLGSGLSLS GLVHPELSRS GELAVRALEQ FATVVEAKLI KHKKGIVNEQ FLLQRLADGA IDLYAMVVVL SRASRSLSEG HPTAQHEKML CDTWCIEAAA RIREGMAALQ SDPWELYR NFKSISKALV ERGGVVTSNP ' with or

Tested applications 
（see key）

SDS-PAGE

Expression host 

E. coli

Abreviews 

Customer reviews （see key）

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Application notes 
（see key）

Recommended dilutions
SDS-PAGE: Use at an assay dependent dilution.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Protein length 

615 amino acids.

Molecular weight 

68.5 kDa inclusive of tags.

Research areas 

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Signal Transduction >> Metabolism >> Mitochondrial

Relevance 

ACADVL （acyl-Coenzyme A dehydrogenase, very long chain） catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. It is specific to esters of long-chain and very long chain fatty acids such as palmitoyl-CoA and stearoyl-CoA. Deficiencies in ACADVL are associated with reduced myocardial fatty acid beta-oxidation and cardiomyopathy.

Purity 

>90% by SDS-PAGE

Purification notes 

ab98234 was purified using conventional chromatography techniques.

Storage buffer 

Preservative: None
Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM EDTA, 1mM DTT, pH 8.0

E. C. number 

1.3.99.-

Uniprot accession 

P49748

Form 

Liquid

Concentration 

0.500 mg/ml

Storage instructions 

Store at +4°C short term （1-2 weeks）. Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.