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Anti-HLA-B27 （EP-4）
最近更新時間：2012-7-25
提 供 商：上海研生實業有限公司資料大小：25.5KB
文件類型：WORD 文檔下載次數：492次
資料類型：未知文件瀏覽次數：878次
Catalog Number : DZ77217 Quantity size : 0.1ml （dilute with pH 7.4 0.01 M PBS or antibody diluent ）
Background: Major histocompatibility complex （MHC） molecules form an integral part of the immune response system. They are cell-surface receptors that bind pep- tides and present them to T lymphocytes. Human leukocyte antigens （HLAs） are polymorphic members of the MHC family that are specifically involved in the presentation of antigens to the T cell receptor. There are two classes of HLA antigens: class I （HLA-A, HLA-B and HLA-C） and class II （HLA-D）. Class I molecules are expressed in nearly all cells and play a central role in the immune system by presenting peptides derived from the endoplasmic reticu- lum. The differential structural properties of MHC class I and class II mole- cules account for their respective roles in activating different populations of T lymphocytes. HLA-B encodes a membrane anchored heavy chain which hetero-dimerizes with a light chain.
Specificity : Anti-HLA-B27 （EP-4）
– anti-HLA-B27 is a mouse polyclonal antibody unconjugated
– specific for HLA-B27 antibody of human
– epitope mapping near the amino terminus of HLA-B27 antigen of human
– use for western blotting, elisa, immunoprecipitation and immunohistochemistry
– Protein A affinity chromatography purification, purity :>95%
– Isotype: IgM
– mol wt: 38kDa
Application :
– Western blotting 1:100-500
– Immunohistochemistry 1:100-500
– ELISA 1:500-1000
– Optimal working dilutions must be determined by the end user.
Storage: Anti-HLA-B27 （EP-4）
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.