| 英文名稱 | Anti-CD14 Polyclonal Antibody |
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| 宿主 | Rabbit |
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| 別名 | CD14;Monocyte differentiation antigen CD14;CD14 molecule;LPS-R;Mo2 |
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| 應用 | WB |
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| 稀釋比例 | WB 1:3000. |
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| 交叉反應 | Human |
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| 蛋白分子量 | 40kDa |
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| Gene ID | 929 |
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| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
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| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
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| 純化方法 | Affinity purification |
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| 亞型 | IgG |
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| 免疫原 | A synthetic peptide of human CD14 |
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| 性狀 | 液體 |
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| Public Immunogen Range | A synthetic peptide of human CD14 |
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| Subcellular Locations | Cell membrane GPI-anchor Lipid-anchor Secreted |
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| Swiss Prot | P08571 |
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| 克隆類型 | Polyclonal Antibody |
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| 背景資料 | Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. |
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