abbit Anti –c-Met/HGFR

                   （hepatocyte growth factor receptor）

Quantity size :   0.1ml  （Reconstitued with 200ul pH 7.4  0.01 M PBS or diluent of antibody）

Background:   c-Met （met proto-oncogene） （hepatocyte growth factor receptor）, isoform ; CRA_b; （HGF receptor） （Scatter factor receptor） （SF receptor） （HGF/SF receptor） （Met proto-oncogene tyrosine kinase） receptor protein tyrosine kinase. The Met receptor tyrosine kinase is the prototypical member of a small subfamily of growth factor receptors that when activated, induces mitogenic, motogenic, and morphogenic cellular responses. The ligand for c-met is hepatocyte growth factor/scatter factor （HGF/SF） and while normal HGF/SF-Met signaling is required for embryonic development, abnormal c-met signaling has been strongly implicated in tumorigenesis, particularly in the development of invasive and metastatic phenotypes.

 Specificity :    · anti- c-Met is a rabbit polyclonal antibody unconjugated

                · specific for c-Met of human dog, rat and mouse

                · epitope mapping in the N-terminus of c-Met of human dog, rat and mouse

· use for western blotting, elisa, immunoprecipitation

                   and immunohistochemistry

· Protein G affinity chromatography purification, purity :>95%

· Isotype: IgG

· mol wt: 142kDa

Application:     · WB：1：200-500

· ELISA：1：500-1000

· IHC ：1：200-500

· Optimal working dilutions must be determined by the end user.

Storage:        Store at –20 ºC for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20ºC. When reconstituted in sterile pH 7.4  0.01 M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ºC.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications