亚洲国产成人精品久久久国产成人一区二区三区综合区精品久久久中文字幕一区_欧美日韩精品久久久免费观看成人国产亚洲欧美成人综合网_久久久久国产欧美日韩精品一区二区三区_亚洲国产成人精品无码区在线观看_亚洲日韩国产成人高清视频不卡在线_精品欧美国产一区二区三区不卡

CYT-358

重組小鼠γ干擾素（rmIFN-γ）

20μg/100μg/1mg

Prospec

Background:
	The major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly by T-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. The synthesis of IFN-gamma is induced, among other things, by Interleukin-2 , FGF-basic , and EGF .
	Description :
	Recombinant Murine IFN-gamma produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 134 amino acids and having a molecular mass of 15601 Dalton. Recombinant IFN-gamma is purified by proprietary chromatographic techniques.
	Physical Appearance:
	Sterile Filtered White lyophilized （freeze-dried） powder.
	Formulation:
	IFN-g was lyophilized from 0.5X PBS pH-7.2.
	Solubility:
	It is recommended to reconstitute the lyophilized mouse IFN-gamma in sterile 18MΩ-cm H₂O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.
	Stability:
	Lyophilized IFN-g although stable at room temperature for 3 weeks, should be stored desiccated below -18⁰C. Upon reconstitution IFN-g should be stored at 4⁰C between 2-7 days and for future use below -18⁰C. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please avoid freeze-thaw cycles.
	Purity:
	Greater than 95.0% as determined by: （a） Analysis by RP-HPLC. （b） Anion-exchange FPLC. （c） Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
	Amino acid sequence:
	The sequence of the first five N-terminal amino acids was determined and was found to be Met-His-Gly-Thr-Val.
	Dimers and aggregates:
	Less than 1% as determined by silver-stained SDS-PAGE gel analysis.
	Biological Activity:
	ProSpec's Recombianant Murine Interferon gamma is fully biologically active when compared to standard. The specific activity as determined by the cytopathic affect inhibition assay with murine NIH 3T3 cells chalenged with EMC virus was < 0.1 ng/ml, corresponding to a specific activity of 1 x 10⁷IU/mg.
	Endotoxin:
	Less than 0.1 ng/µg （IEU/µg） of IFN-gamma.
	Protein content:
	Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm . 2. Analysis by RP-HPLC, using a standard solution of IFN-gamma as a Reference Standard.
	Usage:
	Prospec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.