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R,S-SULFORAPHANE, HIGH PURITY

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SULFORAPHANE

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深圳市明博林生物科技有限公司(簡稱:深圳明博林)成立于2006年,其前身是深圳市博林化工有限公司,是美國LKT Laboratories,Inc在中國設立的子公司,承擔其在中國及東南亞的一切商務活動。目前主要銷售LKT及其代理的一些歐美試劑。截止目前代理銷售的歐美品牌有:LKT、Matreya、ChemieTek、Focus Biomolecules、Peptides、Neogen、AMSbio、AG Scientific、Acesobio和Active Biochem等。

科研試劑

R,S-Sulforaphane is a synthetic isothiocyanate. R-Sulforaphane is the naturally-occurring isomer, found in broccoli. This compound exhibits antioxidative, neuroprotective, anti-inflammatory, anti-atherosclerotic, neuromodulatory, cardioprotective, anticoagulant, antibiotic, anticancer chemotherapeutic, and chemopreventive activities; research suggests that the R-isomer may be more bioactive than the S-isomer. R,S-Sulforaphane induces activity and expression of phase II enzymes, inhibits the aryl hydrocarbon receptor, and downregulates expression of HDACs and STAT5. In cellular and animal models of melanoma, this compound inhibits tumor growth and cell proliferation. R,S-Sulforaphane also induces autophagy. In animal models of Alzheimer’s disease, R,S-sulforaphane lessens cognitive impairment. Additionally, this compound increases activity of Nrf2 and expression of catalase, protecting against UV-induced oxidative damage in ex vivo models. In other animal models, R,S-sulforaphane inhibits TNF-α-induced adhesion of monocytes to epithelial cells and decreases levels of VCAM-1. In myocytes, this compound prevents angiotensin II-induced hypertrophy. Additionally, R,S-sulforaphane inhibits plaet aggregation by suppressing PI3K/Akt signaling. R,S-Sulforaphane also displays antibacterial efficacy against Escherichia. Please note: This compound is a neat liquid at room temperature, clear to slightly yellow in color. It is not dissolved in solvent. In small quantities the material will coat the sides of the ampule it is shipped in and may appear to be invisible, or it may be trapped in the tip of the ampule. Wash the upper and lower parts of the ampoule with solvent to ensure all of the material is obtained.

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