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【產品簡介】
【詳細說明】
GaTx1
Selective blocker of CFTR channels(CFTR通道選擇性阻斷劑)
The GaTx1 peptide was originally isolated from the venom of Leiurus quinquestriatus hebraeus. GaTx1 is a potent and selective inhibitor of CFTR, an anion selective channel belonging to the ABC transporter superfamily. It was shown to block CFTR channels in a state dependent manner by acting from the internal face of the channel and it is supposed to be a non competitive inhibitor of ATP-dependent channel gating. GaTx1 is a valuable tool to explore the function of CFTR.
GaTx1 技術資料
氨基酸序列：
Cys1-Gly-Pro-Cys4-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys15-Ala-Glu-Cys18-Cys19-Gly-Gly-Ile-Gly-Lys-Cys25-Tyr-Gly-Pro-Gln-Cys30-Leu-Cys32-Asn-Arg-NH2
二硫鍵： Cys1-Cys18, Cys4-Cys25, Cys15-Cys30, and Cys19-Cys32
長度 (aa)：34
分子式： C147H224N46O47S96
分子量： 3674.2 Da
外觀：White lyophilized solid
可溶性： water and saline buffer
CAS 號： not available
來源：Synthetic
純度： > 98 %
產品信息
13GTX001-00100 | GaTx1 | 0.1mg |
13GTX001-00500 | GaTx1 | 0.5mg |
13GTX001-01000 | GaTx1 | 1mg |